Peripheral Ossifying Fibroma Evolved Off Pyogenic Granuloma

Peripheral Ossifying Fibroma Evolved Off Pyogenic Granuloma

Cite this article since the: Godinho Grams V, Silva C A great, Noronha B R, mais aussi al. () Peripheral Ossifying Fibroma Changed Away from Pyogenic Granuloma. Cureus 14(1): e20904. doi:/cureus.20904


The goal of the present blog post is to introduce the new logical case of a big peripheral ossifying fibroma you to definitely progressed regarding a in past times diagnosed pyogenic granuloma from inside the an effective fifty-year-old woman. The individual was referred to have remedy for a good lesion along side buccal and you can palatal gingiva near the left top earliest molar. It had been purplish-red-colored into the color, around step three cm when you look at the diameter, having a mellow surface, good pedicled and you will hemorrhaging ft, having seven years of development, and diagnosed just like the pyogenic granuloma. Shortly after 36 months from evasion, the individual came back revealing an increase in the brand new lesion and you may difficulty inside food. Medically the fresh new nodule was lobular in features, red during the colour and you will effortless, pediculated, business from inside the consistency, non-hemorrhaging, regarding 5 cm in better expansion, stretching with the maxillary tuberosity. The newest lesion try excised and you may called getting histopathological test, and this triggered the brand new medical diagnosis regarding peripheral ossifying fibroma. The person was implemented for approximately 18 months, prosthetically rehabilitated, having satisfactory recovery no scientific signs and symptoms of reappearance.

The newest you’ll progression out of an excellent pyogenic granuloma to a good peripheral ossifying fibroma was present in this case, according to research by the histopathological change you to took place, toward development of calcified question, fibrous growth, and reduced vascular stuff of initially lesion immediately following three-years.


Pyogenic granuloma (PG) is the second popular reactive lesion of the oral cavity, once inflammatory stringy hyperplasia, the most common reactive lesion. PG gift ideas a well-circumscribed and you can collection of lobular plan, with highest central ships and you may better-shaped peripheral capillary aggregates. Whenever unattended, so it lesion is also proceed through fibrous maturation having ossification and develop for the peripheral ossifying fibroma .

Peripheral ossifying fibroma (POF) try a harmless mesenchymal lesion, predominant on anterior maxillary gingiva of women between your 2nd and you may 3rd ages regarding lives. It’s noticed a beneficial metaplastic procedure that involves the periodontal ligament as a result in order to stress otherwise regional irritants, such biofilm, calculus, defectively modified prostheses, and you may disappointing renovations [dos,3]. The fresh development off PG so you can POF is actually told me with their systematic and histopathological parallels; not, it is essential to observe that only a few POF evolves off an excellent PG. The fresh mineralized parts formed may vary certainly cementum, limbs, and you will dystrophic calcification .

That it statement gifts the fact away from a large peripheral ossifying fibroma that progressed away from an effective lesion in past times identified as pyogenic granuloma during the good 50-year-dated woman.

Instance Presentation

A good fifty-year-dated hypertensive woman is described the latest Dental and Maxillofacial Functions and you can Traumatology outpatient clinic of the Mato Grosso Cancer tumors Healthcare, Cuiaba, Brazil, having treatment of an effective maxillary lesion, recognized because PG, just like the demonstrated by histopathological study of an incisional biopsy performed in the past. Brand new tiny breakdown consisted of good fragment away from mucosa protected by stratified hyperparakeratinized squamous epithelium, which have regions of acanthosis and you can a lot of time projections, spongiosis, exocytosis, and ulceration. New lamina propria was shaped of the dense connective structure, having aspects of serious cellularity and you will expansion off endothelial structure being indexed, having beginning away from vascular room and you will regions of severe chronic inflammatory infiltrate with hemorrhagic parts (Figure step one).

Shape 1: Histological picture of pyogenic granuloma demonstrating hyperparakeratinized stratified squamous epithelium, with aspects of acanthosis and enough time forecasts.

Lamina propria shaped by thicker connective tissue, noting aspects of intense cellularity and you can growth off endothelial tissues, having beginning off vascular places and you may areas of intense chronic inflammatory penetrate that have hemorrhagic parts (Haemotoxylin and you will Eosin, 100x).

Medically, she presented a great nodule along the buccal and you can palatal gingiva romantic to the left upper first molar, as much as step three cm into the diameter, with a delicate body, purplish-red color, pedicled and hemorrhaging base with eight several years of development. On the suggestion, there can be and the prognosis from big chronic periodontitis, observing, for the intraoral bodily examination, poor dental health and you will generalized tooth versatility.

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